vaginal microbiome Research

I am completing my research as a PhD candidate at the in the Ravel lab at the University of Maryland / Institute for Genome Science (IGS) in Baltimore, MD, USA. in which I explored host-microbial interactions in the human vaginal microbiome. I applied machine learning algorithms to prioritize miRNAs for further experimentation. I am currently preparing a manuscript. Stay tuned! 

Jacques and I recently published a review article in the Journal of Physiology: 

Smith, S. B. and Ravel, J. (2017), The vaginal microbiota, host defence and reproductive physiology. J Physiol, 595: 451–463. doi:10.1113/JP271694

pan Respiratory Viral & bacterial projects

Along with collaborators at GlaxoSmithKline Pharmaceuticals and Drexel University, I computationally discovered common host responses across seven and two different respiratory viral and bacterial pathogens, respectively:

Smith SB, Dampier W, Tozeren A, Brown JR, Magid-Slav M (2012) Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis  PLoS ONE 7(3): e33174. doi:10.1371/journal.pone.0033174

Smith SB, Magid-Slav M, Brown JR (2013) Host Response to Respiratory Bacterial Pathogens as Identified by Integrated Analysis of Human Gene Expression Data. PLoS ONE 8(9): e75607. doi:10.1371/journal.pone.0075607

A Showcase of other projects

I have a myriad of other projects in which I designed experiments and applied computational methods:

  • Designed & Implemented MySQL databases to manage major projects.
  • Identifyed Novel miRNA in Arabidopsis Thaliana
  • Safety Assessment Study at AstraZeneca Pharmaceuticals
  • Design & Implementation of a Brain-Computer Interface
  • Image Recognition using a Neural Network
  • Research Development Study at Lyophilization Technology, Incorporated